E.W. "Al" Thrasher Awards focus on projects that are changing pediatric clinical care. Each award is a novel approach to problems plaguing pediatrics. The award is open to applications focusing on any disease or topic within the umbrella of pediatrics, both in and outside the United States.
Ideal applications for the Thrasher Award address significant health problems, offering the potential for practical solutions to these problems. Typically, the primary outcome is a health outcome in children. Solutions should be innovative and have the potential for broad applicability with low barriers to implementation. Projects with a shorter distance to clinical applicability are given priority. Hypothesis-driven research is critical, exploratory, or hypothesis-generating research will not be competitive.
For projects focused on improving disease diagnosis, please ensure that there are well researched, effective treatment options available to patients upon diagnosis.
Thrasher's focus is on child outcomes- we want to fund science that will make meaningful progress in the way diseases are diagnosed and treated. Competitive grants often, but are not required to, focus on severe or high incidence diseases. The aims include child driven outcomes, and the proposals are far enough along in the research process to make a clinical difference within a few years.
If the submitted grant includes study sites outside the Principal Investigator home country, applications must include a co-investigator from each country included as a study site. Capacity building and buy in from local leaders and clinicians is critical to our mission for improving child health.
Please feel free to reach out to out Research Managers with inquiries about project ideas or proposal aims. We are happy to discuss specifics and give you an idea of what will be competitive.
Principal Investigators must be qualified in terms of education and experience to conduct research. A doctoral-level degree is required. There are no citizenship or residency requirements. The Fund is open to applications from institutions both inside and outside the United States.
The Fund uses a two-step process for E.W. "Al" Thrasher Awards. The first step is the submission of a Concept Paper. These Concept Papers are reviewed by the Fund's staff. Applicants whose concepts generally fit with the current priorities of the Fund are invited to submit a full proposal. Applicants have about 10 weeks to submit a full proposal from the date of invitation. Full proposals are reviewed by external peer reviewers with specific expertise in the subject being proposed. Proposals recommended by peer reviewers are considered by the Fund's Committees. The Committees meet to make funding decisions in March and September.
Timelines are generally the same from year to year, specific dates are found below:
Concept Submission Deadline | January 18, 2024 (Noon Mountain Time) |
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Concept Paper Decisions | By February 13, 2024 |
Full Proposal Submission Deadline | By April 26, 2024 (Noon Mountain Time) |
Peer Review Completion | Approx. June 2024 |
Response to Peer Review | Approx. July 2024 |
Peer Review of Revision | Approx. August 2024 |
Proposal Materials to Advisory Committee | August 16, 2024 |
Proposal Materials to Executive Committee | August 30, 2024 |
Final Decision | September 13, 2024 |
Concept Submission Deadline | July 16, 2024 (Noon Mountain Time) |
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Concept Paper Decisions | By August 13, 2024 |
Full Proposal Submission Deadline | By October 22, 2024 (Noon Mountain Time) |
Peer Review Completion | Approx. December 2024 |
Response to Peer Review | Approx. January 2025 |
Peer Review of Revision | Approx. February 2025 |
Proposal Materials to Advisory Committee | February 14, 2025 |
Proposal Materials to Executive Committee | February 28, 2025 |
Final Decision | March 14, 2025 |
Concept Submission Deadline | January 14, 2025 (Noon Mountain Time) |
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Concept Paper Decisions | By February 6, 2025 |
Full Proposal Submission Deadline | By April 17, 2025 (Noon Mountain Time) |
Peer Review Completion | Approx. June 2025 |
Response to Peer Review | Approx. July 2025 |
Peer Review of Revision | Approx. August 2025 |
Proposal Materials to Advisory Committee | August 15, 2025 |
Proposal Materials to Executive Committee | August 29, 2025 |
Final Decision | September 12, 2025 |
Concept Submission Deadline | July 15, 2025 (Noon Mountain Time) |
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Concept Paper Decisions | By August 8, 2025 |
Full Proposal Submission Deadline | By October 30, 2025 (Noon Mountain Time) |
Peer Review Completion | Approx. December 2025 |
Response to Peer Review | Approx. January 2026 |
Peer Review of Revision | Approx. February 2026 |
Proposal Materials to Advisory Committee | February 13, 2026 |
Proposal Materials to Executive Committee | February 27, 2026 |
Final Decision | March 14, 2026 |
The grant amount is based on the actual budgetary needs of the project. The duration of the project can be up to three years. Indirect costs are no more than 7% of direct costs. In 2012-2016 the median grant was $370,000. Grants are not given over $550,000.
Investigators and co-investigators in need of salary support may apply for no more than 20 percent, based on a 40-hour work week. The Fund limits the maximum salary upon which an individual can request salary support. The maximum amount will be based on the NIH guidelines for salary support. Salaries for support staff, students, and others do not have the 20% restriction.
Requests for purchase of major equipment (items >$4,000) are discouraged and rarely funded.
The final budget should be consistent with the budget amount proposed in the approved Concept Paper. All exceptions must be cleared through the Fund.
The Fund is open to a variety of different opportunities that include co-funding of projects with different funding sources. The portion of the project proposed to Thrasher should be discrete, although it may be dependent on portions of the study funded from other sources such as testing of additional hypotheses from an ongoing trial. Proposals requesting Thrasher to commit money to a larger pool of funding with no distinct project proposed to Thrasher will not be funded. Co-funding requests are dealt with on a case-by-case-basis. Interested applicants may consult with one of the Fund's Research Managers to discuss specifics of their individual situations.
We invite our applicants to create a PowerPoint video, no more then three and a half minutes, to be submitted at the same time as the proposal revision after peer review. These videos should convey the need for the project, focusing on the research gap and potential for improved clinical care. They should also cover the hypothesis, aims, and study design of the proposal.
Videos are played in Committee Meetings as each project is discussed. We hope that they allow applicants to convey what they see as the most important aspects of the project and make a case for funding.
Instructions can be found in the "Downloads" section of this page.